Anti-Human/Rat PKP2 Polyclonal Antibody

PKP2多克隆抗体

This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This gene product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13.
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基本信息

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货号 PA05601
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from the C-terminal region of human Plakophilin 2
特异性 Detected in heart right ventricle (at protein level). Widely expressed. Found at desmosomal plaques in simple and stratified epithelia and in non-epithelial tissues such as myocardium and lymph node follicles. In most stratified epithelia found in the desmosomes of the basal cell layer and seems to be absent from suprabasal strata.
亚型 IgG
反应性 Human,Rat
克隆
Uniprot Q99959
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, ELISA 1:20000
配方
应用范围 WB,ELISA
别名 ARVD 9,ARVD9,PKP 2,PKP2,PKP2,Plakophilin-2,Plakophilin2
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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