Anti-Human/Rat HYAL3 Polyclonal Antibody

HYAL3多克隆抗体

This gene encodes a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon.
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基本信息

数据文档 查看数据文档
货号 PA09749
规格 100μl
宿主 Rabbit
免疫原 Recombinant protein of human HYAL3
特异性 Bone marrow, testis and kidney. Isoform 4 is detected in all bladder tumor and prostate tumor cells.
亚型 IgG
反应性 Human,Rat
克隆
Uniprot O43820
浓度 0.2 mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:50-1:200
配方
应用范围 WB,IHC,ELISA
别名 Hyal-3,HYAL3,HYAL3,Hyaluronidase 3,Hyaluronidase-3,Hyaluronoglucosaminidase 3,Hyaluronoglucosaminidase-3,LUCA-3,LUCA14,LUCA3,Lung carcinoma protein 3,Minna14
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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