Anti-Human/Rat HDAC3 Polyclonal Antibody

HDAC3多克隆抗体

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
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基本信息

数据文档 查看数据文档
货号 PA07862
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide of human HDAC3
特异性 Widely expressed.
亚型 IgG
反应性 Human,Rat
克隆
Uniprot O15379
浓度 0.5 mg/mL
推荐稀释度 WB 1:200-1:1000
配方
应用范围 WB,ELISA
别名 HD3,HDAC 3,HDAC3,HDAC3,Histone deacetylase 3,RPD3 2,RPD3,RPD3-2,SMAP45
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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