Anti-Human/Rat CDKL1 Polyclonal Antibody

CDKL1多克隆抗体

The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated by the MAP kinases ERK 1 and ERK 2. ERK proteins are regulated by dual phosphorylation at specific tyrosine and threonine sites mapping within a characteristic Thr-Glu-Tyr motif. The protein kinase p56 KKIAMRE is distantly related to the MAP kinase group of proteins and is closely related to p42 KKIALRE. KKIAMRE is predominantly expressed in testis, kidney, brain and lung. KKIAMRE contains the conserved MAP kinase dual phosphorylation motif in the sequence Thr-Asp-Tyr and is activated by treatment of cells by EGF. However, unlike other MAP kinases, the EGF-stimulated kinase activity does not require phosphorylation of KKIAMRE and KKIALRE in the Thr-Asp-Tyr motif.
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基本信息

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货号 PA04679
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from the C-terminal region of human KKIALRE
特异性 Highly expressed in kidney, and to a lower extent in ovary.
亚型 IgG
反应性 Human,Rat
克隆
Uniprot Q00532
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
配方
应用范围 WB,IHC-p,ELISA
别名 CDC 2 related kinase 1,CDC 2 related kinase,CDC2 related kinase 1,CDC2 related kinase,CDK L1,CDKL 1,cdkl1,CDKL1,Cyclin dependent kinase like 1,cyclin-dependent kinase-like 1 (CDC2-related kinase),Cyclin-dependent kinase-like 1,EC 2.7.11.22,KKIALRE,p42,Protein kinase p42 KKIALRE,Serine/threonine protein kinase KKIALRE,Serine/threonine-protein kinase KKIALRE
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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