Anti-Human PLAUR Polyclonal Antibody

PLAUR多克隆抗体

This gene encodes the receptor for urokinase plasminogen activator and, given its role in localizing and promoting plasmin formation, likely influences many normal and pathological processes related to cell-surface plasminogen activation and localized degradation of the extracellular matrix. It binds both the proprotein and mature forms of urokinase plasminogen activator and permits the activation of the receptor-bound pro-enzyme by plasmin. The protein lacks transmembrane or cytoplasmic domains and may be anchored to the plasma membrane by a glycosyl-phosphatidylinositol (GPI) moiety following cleavage of the nascent polypeptide near its carboxy-terminus. However, a soluble protein is also produced in some cell types. Alternative splicing results in multiple transcript variants encoding different isoforms. The proprotein experiences several post-translational cleavage reactions that have not yet been fully defined.
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基本信息

数据文档 查看数据文档
货号 PA12601
规格 100μl
宿主 Rabbit
免疫原 Recombinant protein of human PLAUR
特异性 Expressed in neurons of the rolandic area of the brain (at protein level). Expressed in the brain.
亚型 IgG
反应性 Human
克隆
Uniprot Q03405
浓度 0.2 mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:50-1:200
配方
应用范围 WB,IHC,ELISA
别名 CD 87,CD87,CD87 antigen,MO 3,MO3,Monocyte activation antigen Mo3,Plasminogen activator receptor urokinase,Plasminogen activator urokinase receptor,PLAUR,U PAR,u plasminogen activator receptor,U-PAR,u-plasminogen activator receptor form 2,UPA receptor,uPAR,UPAR,Urinary plasminogen activator receptor,URKR,Urokinase plasminogen activator receptor,Urokinase plasminogen activator surface receptor,urokinase-type plasminogen activator (uPA) receptor
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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