Anti-Human Phospho-PTK6 (Tyr447) Polyclonal Antibody

Phospho-PTK6 (Tyr447)多克隆抗体

The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase whicHuman, Mouseay function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants.
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基本信息

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货号 PA01735
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from human Brk around the phosphorylation site of Y447.
特异性 Epithelia-specific. Very high level in colon and high levels in small intestine and prostate, and low levels in some fetal tissues. Expressed at low level in some breast tumors, but not in normal breast. Also found in melanocytes. Not expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
亚型 IgG
反应性 Human
克隆
Uniprot Q13882
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, IF 1:200-1:1000, ELISA 1:5000
配方
应用范围 WB,IF,ELISA
别名 Breast tumor kinase,Breast tumour kinase,Protein tyrosine kinase 6,Protein-tyrosine kinase 6,Ptk6,PTK6,Tyrosine protein kinase BRK,Tyrosine-protein kinase BRK
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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