Anti-Human Phospho-ERBIN (Tyr1104) Polyclonal Antibody

Phospho-ERBIN (Tyr1104)多克隆抗体

This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.ERBIN (Erbb2 Interacting Protein) is a Protein Coding gene. Diseases associated with ERBIN include Congenital Muscular Dystrophy Due To Lmna Mutation. Among its related pathways are NLR Proteins and Signaling by GPCR. An important paralog of this gene is LRRC7.
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基本信息

数据文档 查看数据文档
货号 PA01552
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from human Erbin around the phosphorylation site of Tyr1104
特异性 Highly expressed in brain, heart, kidney, muscle and stomach, followed by liver, spleen and intestine.
亚型 IgG
反应性 Human
克隆
Uniprot Q96RT1
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, ELISA 1:10000
配方
应用范围 WB,ELISA
别名 Densin-180-like protein,Erbb2-interacting protein,Erbb2ip,Erbin,LAP2,LAP2,Protein LAP2
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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