Anti-Human PEG10 Polyclonal Antibody

PEG10多克隆抗体

This is a paternally expressed imprinted gene that encodes transcripts containing two overlapping open reading frames (ORFs), RF1 and RF1/RF2, as well as retroviral-like slippage and pseudoknot elements, which can induce a -1 nucleotide frame-shift. ORF1 encodes a shorter isoform with a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons. The longer isoform is the result of -1 translational frame-shifting leading to translation of a gag/pol-like protein combining RF1 and RF2. It contains the active-site consensus sequence of the protease domain of pol proteins. Additional isoforms resulting from alternatively spliced transcript variants, as well as from use of upstream non-AUG (CUG) start codon, have been reported for this gene. Increased expression of this gene is associated with hepatocellular carcinomas.
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基本信息

数据文档 查看数据文档
货号 PA07047
规格 100μl
宿主 Rabbit
免疫原 Recombinant protein of human PEG10
特异性 Expressed in the cytotrophoblast layer but not in the overlying syncytiotrophoblast of the placenta. Expressed in prostate and breast carcinomas but not in normal breast and prostate epithelial cells. Expressed in the HepG2 cell line (at protein level). Expressed in brain, liver, spleen, kidney, thymus, lung, ovary, testis, reactive lymph node, skeletal muscle, adipose tissue and placenta. Expressed in pancreatic and hepatocellular carcinomas (HCC).
亚型 IgG
反应性 Human
克隆
Uniprot Q86TG7
浓度 0.2 mg/mL
推荐稀释度 WB 1:200-1:1000
配方
应用范围 WB,ELISA
别名 AA407948,Edr,Embryonal carcinoma differentiation regulated,Embryonal carcinoma differentiation-regulated protein,HB 1,HB1,KIAA1051,Mammalian retrotransposon-derived protein 2,Mar2,Mart2,MEF3 like 1,MEF3-like protein 1,MEF3L,MEF3L1,MyEF 3,Myelin expression factor 3-like protein 1,Paternally expressed 10,Paternally expressed gene 10 ORF1,Paternally expressed gene 10 protein,Peg10,PEG10 protein,PEG10,Putative uncharacterized protein PEG10,Retrotransposon gag domain containing 3,Retrotransposon gag domain-containing protein 3,Retrotransposon-derived gag-like polyprotein,Retrotransposon-derived protein PEG10,RGAG3,Ty3/Gypsy-like protein
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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