Anti-Human NANOS1 Polyclonal Antibody

NANOS1多克隆抗体

NANOS1 (Nanos C2HC-Type Zinc Finger 1) is a Protein Coding gene. Diseases associated with NANOS1 include Spermatogenic Failure 12. GO annotations related to this gene include RNA binding and translation repressor activity. An important paralog of this gene is NANOS3.This gene encodes a CCHC-type zinc finger protein that is a member of the nanos family. This protein co-localizes with the RNA-binding protein pumilio RNA-binding family member 2 and may be involved in regulating translation as a post-transcriptional repressor. Mutations in this gene are associated with spermatogenic impairment.
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基本信息

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货号 PA04503
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from Nanos Homologue 1 (NANOS1)
特异性 Testis and ovary (at protein level). Predominantly expressed in testis. Specifically expressed during germline development. In adult tissues, it is mainly expressed in spermatogonia, the stem cells of the germline. Also expressed during meiosis in spermatocytes. Not present in late, post-meiotic stage germ cells. Expressed in fetal ovaries, while it is weakly or not expressed in mature postmeiotic oocytes, suggesting that it may be expressed in premeiotic female germ cells. Expressed at high levels only in the E-cadherin deficient cell lines. Highly expressed in lung carcinomas and mostly detected in invasive tumor cells and its expression correlates with tumor aggressiveness.
亚型 IgG
反应性 Human
克隆
Uniprot Q8WY41
浓度 1mg/mL
推荐稀释度 WB 1:500-2000, ELISA 1:10000-20000
配方
应用范围 WB,IHC-p,ELISA
别名 EC Rep1a,EC_Rep1a,NANO1,NANOS 1,Nanos homolog 1 (Drosophila),Nanos homolog 1,NANOS1,Nos 1,NOS-1,Nos1,OTTHUMP00000046853,Rep 1a,Rep1a
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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