Anti-Human/Mouse TNIP3 Polyclonal Antibody

TNIP3多克隆抗体

TNIP3, which called LIND, that was upregulated in monocytes infected with Listeria monocytogenes. The predicted 325-amino acid protein contains 3 coiled-coil domains and is most likely localized to the nucleus. Binds to zinc finger protein TNFAIP3 and inhibits NF-kappa-B activation induced by tumor necrosis factor, Toll-like receptor 4 (TLR4), interleukin-1 and 12-O-tetradecanoylphorbol-13-acetate. Overexpression inhibits NF-kappa-B-dependent gene expression in response to lipopolysaccharide at a level downstream of TRAF6 and upstream of IKBKB. NF-kappa-B inhibition is independent of TNFAIP3 binding.
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基本信息

数据文档 查看数据文档
货号 PA08398
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide of human TNIP3
特异性 Highly expressed in lung, lymph node, thymus and fetal liver. Expressed at lower levels in bone marrow, brain, kidney, spleen, leukocytes and tonsils. Could be detected in heart, salivary gland, adrenal gland, pancreas, ovary and fetal brain. High levels detected in liver, colon, small intestine, muscle, stomach, testis, placenta, thyroid, uterus, prostate, skin and PBL.
亚型 IgG
反应性 Human,Mouse
克隆
Uniprot Q96KP6
浓度 0.4 mg/mL
推荐稀释度 WB 1:200-1:1000
配方
应用范围 WB,ELISA
别名 A20 binding inhibitor of NF kappa B activation 3,ABIN 3,ABIN 3 beta,FLJ21162,LIND,Listeria induced,Listeria induced gene protein,TNFAIP3 interacting protein 3,TNFAIP3 interacting protein 3 beta,TNIP3,TNIP3 beta
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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