Anti-Human/Mouse SWAP70 Polyclonal Antibody

SWAP70多克隆抗体

Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion (By similarity).
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基本信息

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货号 PA07478
规格 100μl
宿主 Rabbit
免疫原 Fusion protein of human SWAP70
特异性 Expressed only in mature B-cells including those associated with mucosa-associated tissue and bronchus-associated tissue (PubMed:10681448). Widely expressed. Abundant in spleen, and fairly abundant in kidney, lung and liver. Also found in monocytes and macrophages (PubMed:12925760).
亚型 IgG
反应性 Human,Mouse
克隆
Uniprot Q9UH65
浓度 0.2 mg/mL
推荐稀释度 IHC 1:25-100, ELISA 1:2000-5000
配方
应用范围 IHC,ELISA
别名 KIAA0640,70kDa,AV235546,FLJ39540,HSPC321,SWA 70 protein,SWAP 70,SWAP switching B-cell complex 70kDa subunit,SWAP-70,SWAP70,Switch associated protein 70,Switch-associated protein 70,SWP70
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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