Anti-Human/Mouse SUFU Polyclonal Antibody

SUFU多克隆抗体

The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.
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基本信息

数据文档 查看数据文档
货号 PA12858
规格 100μl
宿主 Rabbit
免疫原 Recombinant protein of human SUFU
特异性 Ubiquitous in adult tissues. Detected in osteoblasts of the perichondrium in the developing limb of 12-week old embryos. Isoform 1 is detected in fetal brain, lung, kidney and testis. Isoform 2 is detected in fetal testis, and at much lower levels in fetal brain, lung and kidney.
亚型 IgG
反应性 Human,Mouse
克隆
Uniprot Q9UMX1
浓度 0.1 mg/mL
推荐稀释度 WB 1:200-1:1000, IHC 1:15-1:50
配方
应用范围 WB,IHC,ELISA
别名 OTTHUMP00000020374,OTTHUMP00000020377,OTTHUMP00000020379,PRO1280,SU FU,SU(F)U,Su(fu),SUFU,SUFU negative regulator of hedgehog signaling,SUFU,SUFUH,SUFUXL,Suppressor of fused homolog (Drosophila),Suppressor of fused homolog
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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