Anti-Human/Mouse SPDEF Polyclonal Antibody

SPDEF多克隆抗体

The protein encoded by this gene belongs to the ETS family of transcription factors. It is highly expressed in the prostate epithelial cells, and functions as an androgen-independent transactivator of prostate-specific antigen (PSA) promoter. Higher expression of this protein has also been reported in brain, breast, lung and ovarian tumors, compared to the corresponding normal tissues, and it shows better tumor-association than other cancer-associated molecules, making it a more suitable target for developing specific cancer therapies. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
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基本信息

数据文档 查看数据文档
货号 PA07045
规格 100μl
宿主 Rabbit
免疫原 Recombinant protein of human SPDEF
特异性 Expressed in a very restricted set of primarily hormone-regulated epithelial tissues with particularly high expression in the prostate gland. Significantly lower expression is seen in other hormone regulated tissues such as mammary gland, salivary gland, and ovary. Expressed in prostate carcinoma cells.
亚型 IgG
反应性 Human,Mouse
克隆
Uniprot O95238
浓度 1 mg/mL
推荐稀释度 IHC 1:50-1:200
配方
应用范围 IHC,ELISA
别名 bA375E1.3,PDEF,Prostate derived Ets factor,PROSTATE EPITHELIUM SPECIFIC ETS TRANSCRIPTION FACTOR,Prostate epithelium-specific Ets transcription factor,Prostate specific Ets,Prostate-derived Ets factor,Prostate-specific Ets,PSE,RP11-375E1__A.3,SAM POINTED DOMAIN CONTAINING ETS TRANSCRIPTION FACTOR,SAM pointed domain-containing Ets transcription factor,Spdef,SPDEF
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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