Anti-Human/Mouse SKIL Polyclonal Antibody

SKIL多克隆抗体

The protein encoded by this gene is a component of the SMAD pathway, which regulates cell growth and differentiation through transforming growth factor-beta (TGFB). In the absence of ligand, the encoded protein binds to the promoter region of TGFB-responsive genes and recruits a nuclear repressor complex. TGFB signaling causes SMAD3 to enter the nucleus and degrade this protein, allowing these genes to be activated. Four transcript variants encoding three different isoforms have been found for this gene.
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基本信息

数据文档 查看数据文档
货号 PA10567
规格 100μl
宿主 Rabbit
免疫原 Recombinant protein of human SKIL
特异性 Isoform SNON and isoform SNOA are widely expressed. Highest expression is found in skeletal muscle, followed by placenta and lung. Lowest expression in heart, brain and pancreas. Isoform SNOI expression is restricted to skeletal muscle.
亚型 IgG
反应性 Human,Mouse
克隆
Uniprot P12757
浓度 0.4 mg/mL
推荐稀释度 WB 1:200-1:1000, IHC 1:30-1:150
配方
应用范围 WB,IHC,ELISA
别名 OTTHUMP00000213557,OTTHUMP00000213591,OTTHUMP00000213592,OTTHUMP00000213595,SKI like,SKI like oncogene,Ski like protein,SKI like proto oncogene,Ski related oncogene,Ski related oncogene snoN,Ski related protein,Ski-like protein,Ski-related oncogene,Ski-related protein,SKIL,SKIL,SNO,SnoA,SnoI,SnoN
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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