Anti-Human/Mouse/Rat ZFP36L1 Polyclonal Antibody

ZFP36L1多克隆抗体

This gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.ZFP36L1 (ZFP36 Ring Finger Protein Like 1) is a Protein Coding gene. Diseases associated with ZFP36L1 include Sotos Syndrome 1. Among its related pathways are Validated targets of C-MYC transcriptional repression and PI3K / Akt Signaling. GO annotations related to this gene include poly(A) RNA binding and mRNA binding. An important paralog of this gene is ZFP36L2.
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基本信息

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货号 PA06032
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from human TIS11B around the non-phosphorylation site of S92.
特异性 Expressed mainly in the basal epidermal layer, weakly in the suprabasal epidermal layers (PubMed:27182009). Expressed in epidermal keratinocytes (at protein level) (PubMed:27182009). Expressed in osteoblasts (PubMed:15465005).
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot Q07352
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
配方
应用范围 WB,IHC-p,ELISA
别名 Berg36,BRF1,Butyrate response factor 1,C3H1 type-like 1,cMG1,EGF-response factor 1,ERF-1,ERF1,Protein TIS11B,RNF162B,TIS11B,TISB,ZFP36L1,Zinc finger protein 36
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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