Anti-Human/Mouse/Rat YWHAE Polyclonal Antibody

YWHAE多克隆抗体

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene.
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基本信息

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货号 PA11355
规格 100μl
宿主 Rabbit
免疫原 Recombinant protein of human YWHAE
特异性
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot P62258
浓度 0.2 mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:10-1:50
配方
应用范围 WB,IHC,ELISA
别名 MDS, MDCR, KCIP-1, 14-3-3E
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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