Anti-Human/Mouse/Rat TNFRSF11B Polyclonal Antibody

TNFRSF11B多克隆抗体

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand, both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. 
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基本信息

数据文档 查看数据文档
货号 PA12534
规格 100μl
宿主 Rabbit
免疫原 Recombinant protein of human TNFRSF11B
特异性 Highly expressed in adult lung, heart, kidney, liver, spleen, thymus, prostate, ovary, small intestine, thyroid, lymph node, trachea, adrenal gland, testis, and bone marrow. Detected at very low levels in brain, placenta and skeletal muscle. Highly expressed in fetal kidney, liver and lung.
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot O00300
浓度 0.3 mg/mL
推荐稀释度 IHC 1:15-1:50
配方
应用范围 IHC,ELISA
别名 MGC29565,OCIF,OPG,Osteoclastogenesis inhibitory factor,Osteoprotegerin,PDB5,TNF receptor superfamily member 11b,TNFRSF 11B,TNFRSF11B,TR 1,TR1,TR11B,Tumor necrosis factor receptor superfamily member 11B
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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