Anti-Human/Mouse/Rat SLC22A17 Polyclonal Antibody

SLC22A17多克隆抗体

Cell surface receptor for LCN2 (24p3) that plays a key role in iron homeostasis and transport. Able to bind iron-bound LCN2 (holo-24p3), followed by internalization of holo-24p3 and release of iron, thereby increasing intracellular iron concentration and leading to inhibition of apoptosis. Also binds iron-free LCN2 (apo-24p3), followed by internalization of apo-24p3 and its association with an intracellular siderophore, leading to iron chelation and iron transfer to the extracellular medium, thereby reducing intracellular iron concentration and resulting in apoptosis.
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基本信息

数据文档 查看数据文档
货号 PA10201
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide of human SLC22A17
特异性 Expressed in brain.
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot Q8WUG5
浓度 0.3 mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:25-1:100
配方
应用范围 WB,IHC,ELISA
别名 24p3 receptor,24p3R,BOCT,BOIT,Brain type organic cation transporter,Brain-type organic cation transporter,hBOIT,Lipocalin-2 receptor,Neutrophil gelatinase associated lipocalin receptor,Neutrophil gelatinase-associated lipocalin receptor,NGAL receptor,NgalR,NGALR2,NGALR3,OTTHUMP00000082690,OTTHUMP00000082691,Potent brain type organic ion transporter,S22AH,Slc22a17,Solute carrier family 22 member 17,Solute carrier family 22 organic cation transporter member 17
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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