Anti-Human/Mouse/Rat SLC12A4 Polyclonal Antibody

SLC12A4多克隆抗体

This gene encodes a member of the SLC12A transporter family. The encoded protein mediates the coupled movement of potassium and chloride ions across the plasma membrane. This gene is expressed ubiquitously. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May contribute to cell volume homeostasis in single cells. May be involved in the regulation of basolateral Cl- exit in NaCl absorbing epithelia.
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基本信息

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货号 PA12683
规格 100μl
宿主 Rabbit
免疫原 Recombinant protein of human SLC12A4
特异性 Ubiquitous. Levels are much higher in erythrocytes from patients with Hb SC and Hb SS compared to normal AA erythrocytes. This may contribute to red blood cell dehydration and to the manifestation of sickle cell disease by increasing the intracellular concentration of HbS. Isoform 1 was not detected in circulating reticulocytes.
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot Q9UP95
浓度 0.3 mg/mL
推荐稀释度 IHC 1:50-1:200
配方
应用范围 IHC,ELISA
别名 Electroneutral potassium chloride cotransporter 1,Electroneutral potassium-chloride cotransporter 1,Erythroid K Cl cotransporter 1,Erythroid K-Cl cotransporter 1,FLJ40489,hKCC 1,hKCC1,KCC 1,KCC1,Potassium transport protein,Potassium/chloride cotransporter 1,S12A4,Slc12a4,Solute carrier family 12 (potassium/chloride transporters) member 4,Solute carrier family 12 member 4
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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