Anti-Human/Mouse/Rat ROCK1 Polyclonal Antibody

ROCK1多克隆抗体

This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity.
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基本信息

数据文档 查看数据文档
货号 PA12656
规格 100μl
宿主 Rabbit
免疫原 Recombinant protein of human ROCK1
特异性 Detected in blood platelets.
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot Q13464
浓度 0.2 mg/mL
推荐稀释度 IHC 1:25-1:100
配方
应用范围 IHC,ELISA
别名 coiled-coil-containing protein kinase 1,coiled-coil-containing protein kinase I,MGC131603,MGC43611,p160 Rhoassociated coiled coil-forming protein kinase,p160 ROCK-1,p160 ROCK1,p160ROCK,PRO0435,Renal carcinoma antigen NY REN 35,Renal carcinoma antigen NY-REN-35,Rho associated coiled coil containing protein kinase 1,Rho associated protein kinase 1,Rho kinase,Rho-alpha kinase,Rho-associated,Rho-associated protein kinase 1,ROCK I,ROCK-I,ROCK1,ROCK1,Rok,rokalpha
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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