Anti-Human/Mouse/Rat PTP4A2 Polyclonal Antibody

PTP4A2多克隆抗体

The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17.
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基本信息

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货号 PA12628
规格 100μl
宿主 Rabbit
免疫原 Recombinant protein of human PTP4A2
特异性 Ubiquitously expressed, with highest levels in skeletal muscle, heart and thymus. Overexpressed in prostate tumor tissue.
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot Q12974
浓度 0.3 mg/mL
推荐稀释度 WB 1:200-1:1000, IHC 1:25-1:100
配方
应用范围 WB,IHC,ELISA
别名 BM 008,EC 3.1.3.48,HH 13,HH13,HH7 2,HU PP 1,HUPP 1,HUPP1,OV 1,OV1,phosphatase of regenerating liver 2,PRL 2,PRL2,Protein tyrosine phosphatase 4a2,protein tyrosine phosphatase IVA,protein tyrosine phosphatase IVA2,Protein tyrosine phosphatase of regenerating liver 2,protein tyrosine phosphatase type IVA 2,Protein tyrosine phosphatase type IVA member 2 isoform 1,protein tyrosine phosphatase type IVA,member 2,PTP (CAAXII),ptp IV1a,ptp IV1b,PTP4A,PTPCAAX2,TP4A2
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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