Anti-Human /Mouse /Rat PSMC5 Polyclonal Antibody

PSMC5多克隆抗体

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. In addition to participation in proteasome functions, this subunit may participate in transcriptional regulation since it has been shown to interact with the thyroid hormone receptor and retinoid X receptor-alpha. Two transcript variants encoding different isoforms have been found for this gene.
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基本信息

数据文档 查看数据文档
货号 PA03166
规格 100μl
宿主 Rabbit
免疫原 Recombinant protein of human PSMC5
特异性
亚型 IgG
反应性 Human ,Mouse ,Rat
克隆
Uniprot P62195
浓度 2.26 mg/mL
推荐稀释度 WB 1:500-1:2000
配方
应用范围 WB
别名 26S protease regulatory subunit 8,26S proteasome AAA-ATPase subunit RPT6,Cim3,MSUG1 protein,p45,p45/SUG,Proteasome 26S ATPase subunit 5,Proteasome 26S subunit ATPase 5,Proteasome prosome macropain 26S subunit ATPase 5,Proteasome subunit p45,PRS8,PSMC5,Rpt6,S8,SUG1,Tat binding protein homolog 10,TBP10,Thyroid hormone receptor interacting protein 1,Thyroid hormone receptor-interacting protein 1,Thyroid receptor interactor 1,TRIP1,TRIP1(SUG1)
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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