Anti-Human/Mouse/Rat PLPP1 Polyclonal Antibody

PLPP1多克隆抗体

The protein encoded by this gene is a member of the phosphatidic acid phosphatase (PAP) family. PAPs convert phosphatidic acid to diacylglycerol, and function in de novo synthesis of glycerolipids as well as in receptor-activated signal transduction mediated by phospholipase D. This protein is an integral membrane glycoprotein, and has been shown to be a surface enzyme that plays an active role in the hydrolysis and uptake of lipids from extracellular space. The expression of this gene is found to be regulated by androgen in a prostatic adenocarcinoma cell line. At least two alternatively spliced transcript variants encoding distinct isoforms have been described.
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基本信息

数据文档 查看数据文档
货号 PA10846
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide of human PPAP2A
特异性 Ubiquitously expressed with highest expression found in prostate. Isoform 1 is predominant in kidney, lung, placenta and liver. Isoform 2 is predominant in heart and pancreas. Found to be down-regulated in colon adenocarcinomas.
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot O14494
浓度 0.4 mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:25-1:100
配方
应用范围 WB,IHC,ELISA
别名 Lipid phosphate phosphohydrolase 1,Lipid phosphate phosphohydrolase 1a,LLP1a,LPP1,LPP1,PAP 2a,PAP-2a,PAP2,PAP2-alpha,PAP2a,PAP2a2,PAP2alpha2,PAPalpha1,Phosphatidate phosphohydrolase type 2a,Phosphatidic acid phosphatase 2a,Phosphatidic acid phosphatase type 2A,Phosphatidic acid phosphohydrolase type 2a,PPAP2A,Type 2 phosphatidic acid phosphatase alpha,Type 2 phosphatidic acid phosphohydrolase
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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