Anti-Human/Mouse/Rat Phospho-Tau (Ser396) Polyclonal Antibody

Phospho-Tau (Ser396)多克隆抗体

Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
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基本信息

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货号 PA01639
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from human Tau around the phosphorylation site of Ser396
特异性 Expressed in neurons. Isoform PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system.
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot P10636
浓度 1mg/mL
推荐稀释度 WB 1:500-2000, IHC 1:50-300, IF 1:50-1:200
配方
应用范围 WB,IHC-p,IF,ELISA
别名 AI413597,AW045860,DDPAC,FLJ31424,FTDP 17,G protein beta1/gamma2 subunit interacting factor 1,MAPT,MAPTL,MGC134287,MGC138549,MGC156663,Microtubule associated protein tau,Microtubule associated protein tau isoform 4,Microtubule-associated protein tau,MSTD,Mtapt,MTBT1,MTBT2,Neurofibrillary tangle protein,Paired helical filament tau,Paired helical filament-tau,PHF tau,PHF-tau,PPND,PPP1R103,Protein phosphatase 1,regulatory subunit 103,pTau,RNPTAU,TAU,TAU,Tauopathy and respiratory failure,included
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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