Anti-Human/Mouse/Rat Phospho-GRK2 (Ser685) Polyclonal Antibody

Phospho-GRK2 (Ser685)多克隆抗体

Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner.
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基本信息

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货号 PA01709
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from human GRK 2 around the phosphorylation site of Ser685
特异性 Expressed in peripheral blood leukocytes.
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot P25098
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, ELISA 1:5000
配方
应用范围 WB,ELISA
别名 ADRBK1,Adrenergic beta receptor kinase 1,ARBK1,BARK,BARK1,Beta adrenergic receptor kinase 1,Beta ARK 1,Beta ARK1,Beta-adrenergic receptor kinase 1,Beta-ARK-1,FLJ16718,G protein coupled receptor kinase 2,G-protein coupled receptor kinase 2,GRK2
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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