Anti-Human/Mouse/Rat Phospho-EIF4E (Ser209) Polyclonal Antibody

Phospho-EIF4E (Ser209)多克隆抗体

Its translation stimulation activity is repressed by binding to the complex CYFIP1-FMR1 (By similarity). Recognizes and binds the 7-methylguanosine-containing mRNA cap during an early step in the initiation of protein synthesis and facilitates ribosome binding by inducing the unwinding of the mRNAs secondary structures. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates the binding to the mRNA cap.
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基本信息

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货号 PA01550
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from human eIF4E around the phosphorylation site of Ser209
特异性
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot P06730
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
配方
应用范围 WB,IHC-p,ELISA
别名 AUTS19,CBP,eIF 4E,eIF 4F 25 kDa subunit,EIF 4F,eIF-4E,eIF-4F 25 kDa subunit,eIF4E,EIF4E1,EIF4EL1,EIF4F,Eukaryotic translation initiation factor 4 E,Eukaryotic translation initiation factor 4E,Eukaryotic translation initiation factor 4E like 1,IF4E,Messanger RNA Cap Binding Protein eIF 4E,MGC111573,mRNA cap binding protein,mRNA cap-binding protein
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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