Anti-Human/Mouse/Rat Phospho-cPLA2 (Ser505) Polyclonal Antibody

Phospho-cPLA2 (Ser505)多克隆抗体

This gene encodes a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic acid which is subsequently metabolized into eicosanoids. Eicosanoids, including prostaglandins and leukotrienes, are lipid-based cellular hormones that regulate hemodynamics, inflammatory responses, and other intracellular pathways. The hydrolysis reaction also produces lysophospholipids that are converted into platelet-activating factor. The enzyme is activated by increased intracellular Ca(2+) levels and phosphorylation, resulting in its translocation from the cytosol and nucleus to perinuclear membrane vesicles.
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基本信息

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货号 PA03817
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from human cPLA2 around the phosphorylation site of Ser505
特异性 Expressed in various tissues such as macrophages, platelets, neutrophils, fibroblasts and lung endothelium.
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot P47712
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
配方
应用范围 WB,IHC-p,IF,ELISA
别名 PLA2G4A,CPLA2,PLA2G4,Cytosolic phospholipase A2,cPLA2,Phospholipase A2 group IVA
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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