Anti-Human/Mouse/Rat Phospho-CHEK2 (Thr387) Polyclonal Antibody

Phospho-CHEK2 (Thr387)多克隆抗体

Regulates cell cycle checkpoints and apoptosis in response to DNA damage, particularly to DNA double-strand breaks. Inhibits CDC25C phosphatase by phosphorylation on 'Ser-216', preventing the entry into mitosis. May also play a role in meiosis. Regulates the TP53 tumor suppressor through phosphorylation at 'Thr-18' and 'Ser-20'.
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基本信息

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货号 PA01776
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from human Chk2 around the phosphorylation site of Thr387
特异性 High expression is found in testis, spleen, colon and peripheral blood leukocytes. Low expression is found in other tissues.
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot O96017
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:5000
配方
应用范围 WB,IHC-p,ELISA
别名 CDS 1,Cds1,Cds1 homolog,Checkpoint kinase 2,Checkpoint like protein CHK2,CHEK 2,Chek2,Chk 2,CHK2 checkpoint homolog (S. pombe),CHK2 checkpoint homolog,CHK2,hCds1,HuCds 1,LFS 2,LFS2,PP1425,RAD 53,RAD53,Rad53 homolog,Serine/threonine protein kinase Chk2,Serine/threonine-protein kinase Chk2
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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