Anti-Human/Mouse/Rat Phospho-AXL (Tyr691) Polyclonal Antibody

Phospho-AXL (Tyr691)多克隆抗体

The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene.AXL (AXL Receptor Tyrosine Kinase) is a Protein Coding gene. Diseases associated with AXL include Lymphocytic Choriomeningitis and Femoral Neuropathy. Among its related pathways are GPCR Pathway and RET signaling. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is MERTK.
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基本信息

数据文档 查看数据文档
货号 PA01828
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from human Axl around the phosphorylation site of Tyr691
特异性 Highly expressed in metastatic colon tumors. Expressed in primary colon tumors. Weakly expressed in normal colon tissue.
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot P30530
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
配方
应用范围 WB,IHC-p,ELISA
别名 Adhesion related kinase,AI323647,Ark,Axl,AXL oncogene,AXL receptor tyrosine kinase,AXL transforming gene,AXL transforming sequence/gene,EC 2.7.10.1,JTK11,Oncogene AXL,Tyro7,Tyrosine protein kinase receptor UFO,Tyrosine-protein kinase receptor UFO,UFO,UFO
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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