Anti-Human/Mouse/Rat PFN2 Polyclonal Antibody

PFN2多克隆抗体

The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.
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基本信息

数据文档 查看数据文档
货号 PA08221
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide of human PFN2
特异性 Highly expressed in brain, skeletal muscle and kidney and less strongly in heart, placenta, lung and liver.
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot P35080
浓度 0.3 mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:25-1:100
配方
应用范围 WB,IHC,ELISA
别名 D3S1319E,PFL,PFN 2,Pfn2,PROF2,Profilin II,Profilin-2,Profilin2,ProfilinII
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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