Anti-Human/Mouse/Rat PERK Polyclonal Antibody

PERK多克隆抗体

Phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2 (EIF2), leading to its inactivation and thus to a rapid reduction of translational initiation and repression of global protein synthesis. Serves as a critical effector of unfolded protein response (UPR)-induced G1 growth arrest due to the loss of cyclin D1.
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基本信息

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货号 PA03877
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from human PERK around the non-phosphorylation site of Thr981.
特异性 Ubiquitous. A high level expression is seen in secretory tissues.
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot Q9NZJ5
浓度 1mg/mL
推荐稀释度 IHC 1:100-1:300, IF 1:50-1:200, ELISA 1:40000
配方
应用范围 IHC-p,IF,ELISA
别名 DKFZp781H1925,E2AK3,EC 2.7.11.1,Eif2ak3,Eukaryotic translation initiation factor 2 alpha kinase 3,Eukaryotic translation initiation factor 2-alpha kinase 3,Heme regulated EIF2 alpha kinase,HRI,HsPEK,Pancreatic eIF2 alpha kinase,Pancreatic eIF2-alpha kinase,PEK,PRKR like endoplasmic reticulum kinase,PRKR-like endoplasmic reticulum kinase,WRS
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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