Anti-Human/Mouse/Rat PDE4B/C/D Polyclonal Antibody

PDE4B/C/D多克隆抗体

PDE4B (Phosphodiesterase 4B) is a Protein Coding gene. Diseases associated with PDE4B include Ocular Hypotension and Acrodysostosis. Among its related pathways are GABAergic synapse and Sweet Taste Signaling. GO annotations related to this gene include ion channel binding and cAMP binding. An important paralog of this gene is PDE4D. PDE4C (Phosphodiesterase 4C) is a Protein Coding gene. Diseases associated with PDE4C include Ocular Hypotension. Among its related pathways are GABAergic synapse and Sweet Taste Signaling. GO annotations related to this gene include 3,5-cyclic-nucleotide phosphodiesterase activity and 3,5-cyclic-AMP phosphodiesterase activity. An important paralog of this gene is PDE4D. PDE4D (Phosphodiesterase 4D) is a Protein Coding gene. Diseases associated with PDE4D include Acrodysostosis 2, With Or Without Hormone Resistance and Acrodysostosis With Multiple Hormone Resistance. Among its related pathways are GABAergic synapse and Sweet Taste Signaling. GO annotations related to this gene include enzyme binding and protein domain specific binding. An important paralog of this gene is PDE4B.
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基本信息

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货号 PA05534
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from human PDE4B/C/D around the non-phosphorylation site of S133/119/190.
特异性 PDE4B is Expressed in brain, heart, lung and skeletal muscle.PDE4C isExpressed in various tissues but not in cells of the immune system.PDE4D is Expressed in colonic epithelial cells (at protein level). Widespread; most abundant in skeletal muscle. Isoform 6 is detected in brain. Isoform 8 is detected in brain, placenta, lung and kidney. Isoform 7 is detected in heart and skeletal muscle.
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
配方
应用范围 WB,IHC-p,ELISA
别名 PDE4B,DPDE4,cAMP-specific 3',5'-cyclic phosphodiesterase 4B,DPDE4,PDE32,PDE4C,DPDE1,cAMP-specific 3',5'-cyclic phosphodiesterase 4C,DPDE1,PDE21,PDE4D,DPDE3,cAMP-specific 3',5'-cyclic phosphodiesterase 4D,DPDE3,PDE43
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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