Anti-Human/Mouse/Rat PC Polyclonal Antibody

PC多克隆抗体

This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.
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基本信息

数据文档 查看数据文档
货号 PA12573
规格 100μl
宿主 Rabbit
免疫原 Recombinant protein of human PC
特异性
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot P11498
浓度 0.2 mg/mL
推荐稀释度 WB 1:200-1:1000
配方
应用范围 WB,ELISA
别名 mitochondrial,OTTHUMP00000235155,OTTHUMP00000235156,PC,PCB,Pcx,PYC,Pyruvate carboxylase,Pyruvate carboxylase mitochondrial,Pyruvic carboxylase
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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