Anti-Human/Mouse/Rat OGT Polyclonal Antibody

OGT多克隆抗体

OGT (O-Linked N-Acetylglucosamine (GlcNAc) Transferase) is a Protein Coding gene. Diseases associated with OGT include Adams-Oliver Syndrome and Spinocerebellar Ataxia 10. Among its related pathways are Circadian rythm related genes and Deubiquitination. GO annotations related to this gene include identical protein binding and phosphatidylinositol-3,4,5-trisphosphate binding. An important paralog of this gene is TMTC3.This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
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基本信息

数据文档 查看数据文档
货号 PA05218
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from human OGT Polyclonal
特异性 Highly expressed in pancreas and to a lesser extent in skeletal muscle, heart, brain and placenta. Present in trace amounts in lung and liver.
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot O15294
浓度 1mg/mL
推荐稀释度 WB 1:500-2000, ELISA 1:10000-20000
配方
应用范围 WB,ELISA
别名 FLJ23071,GlcNAc transferase,HRNT1,MGC22921,O GlcNAc,O GlcNAc transferase p110 subunit,O GlcNAc transferase subunit p110,O linked N acetylglucosamine (GlcNAc) transferase (UDP N acetylglucosamine:polypeptide N acetylglucosaminyl transferase),O linked N acetylglucosamine (GlcNAc) transferase,O linked N acetylglucosamine transferase 110 kDa subunit,O-GlcNAc transferase subunit p110,O-linked N-acetylglucosamine transferase 110 kDa subunit,ogt,OGT1,UDP N acetylglucosamine peptide N acetylglucosaminyltransferase 110 kDa subunit,UDP N acetylglucosamine peptide N acetylglucosaminyltransferase GlcNAc transferase,UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit,UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase,Uridinediphospho N acetylglucosamine:polypeptide beta N acetylglucosaminyl transferase
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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