Anti-Human/Mouse/Rat MYH6/7 Polyclonal Antibody

MYH6/7多克隆抗体

MYH6 (Myosin Heavy Chain 6) is a Protein Coding gene. Diseases associated with MYH6 include Atrial Septal Defect 3 and Cardiomyopathy, Dilated, 1Ee. Among its related pathways are Immune response CCR3 signaling in eosinophils and Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases. GO annotations related to this gene include protein kinase binding and ATPase activity. An important paralog of this gene is MYH7. MYH7 (Myosin Heavy Chain 7) is a Protein Coding gene. Diseases associated with MYH7 include Scapuloperoneal Syndrome, Myopathic Type and Liang Distal Myopathy. Among its related pathways are Cytoskeleton remodeling Regulation of actin cytoskeleton by Rho GTPases and Allograft rejection. GO annotations related to this gene include actin binding and calmodulin binding. An important paralog of this gene is MYH6.Muscle myosin is a hexameric protein containing 2 heavy chain subunits, 2 alkali light chain subunits, and 2 regulatory light chain subunits. This gene encodes the beta (or slow) heavy chain subunit of cardiac myosin. It is expressed predominantly in normal human ventricle. It is also expressed in skeletal muscle tissues rich in slow-twitch type I muscle fibers. Changes in the relative abundance of this protein and the alpha (or fast) heavy subunit of cardiac myosin correlate with the contractile velocity of cardiac muscle.
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基本信息

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货号 PA05013
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide from human protein
特异性 Both wild type and variant Gln-403 are detected in skeletal muscle (at protein level).
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot
浓度 1mg/mL
推荐稀释度 IHC 1:50-200, ELISA 1:10000-20000
配方
应用范围 IHC-p,ELISA
别名 Alpha MHC,MYH6,MyHC alpha,MYHCA,Myosin heavy chain,cardiac muscle alpha isoform,Beta myosin heavy chain,cardiac muscle beta isoform,CMD1S,CMH1,MPD1,MYH7,MYH7,Myhc slow,MyHC-beta,MyHC-slow,MYHCB,Myopathy,distal 1,Myosin heavy chain (AA 1-96),Myosin heavy chain 7,Myosin heavy chain,Myosin heavy chain slow isoform,Myosin heavy chain,cardiac muscle beta isoform,Myosin,heavy chain 7,cardiac muscle,beta,Myosin,heavy polypeptide 7,cardiac muscle,beta,Myosin-7,Rhabdomyosarcoma antigen MU RMS 40.7A,SPMD,SPMM
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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