Anti-Human/Mouse/Rat MYBPC3 Polyclonal Antibody

MYBPC3多克隆抗体

MYBPC3 (Myosin Binding Protein C, Cardiac) is a Protein Coding gene. Diseases associated with MYBPC3 include Cardiomyopathy, Hypertrophic, 4 and Left Ventricular Noncompaction 10. Among its related pathways are Cardiac conduction and Dilated cardiomyopathy. GO annotations related to this gene include identical protein binding and structural constituent of muscle. An important paralog of this gene is MYBPC2.MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.
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基本信息

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货号 PA05200
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from human MYBPC3 Polyclonal
特异性
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot Q14896
浓度 1mg/mL
推荐稀释度 WB 1:500-2000, ELISA 1:10000-20000
配方
应用范围 WB,ELISA
别名 C protein cardiac muscle isoform,C-protein,cardiac muscle isoform,Cardiac MyBP C,Cardiac MyBP-C,Cardiac myosin binding protein C,cardiac-type,CMH4,FHC,MYBP C,MYBPC,MYBPC3,Myosin binding protein C cardiac,Myosin binding protein C cardiac-type,Myosin-binding protein C,myosin-binding protein C cardiac type,MYPC3
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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