Anti-Human/Mouse/Rat/Monkey Phospho-ACO1 (Ser711) Polyclonal Antibody

Phospho-ACO1 (Ser711)多克隆抗体

Aconitase 1, also known as iron regulatory element binding protein 1 (IREB1), is a cytosolic protein which binds to iron-responsive elements (IREs). IREs are stem-loop structures found in the 5' UTR of ferritin mRNA, and in the 3' UTR of transferrin receptor mRNA. The iron-induced binding to the IRE results in repression of translation of ferritin mRNA, and inhibition of degradation of the otherwise rapidly degrading transferrin receptor mRNA. Thus, IREB1 plays a central role in cellular iron homeostasis. It was also shown to have aconitase activity, and hence grouped with the aconitase family of enzymes.
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基本信息

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货号 PA01821
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from human IRP-1 around the phosphorylation site of S711.
特异性
亚型 IgG
反应性 Human,Mouse,Rat,Monkey
克隆
Uniprot P21399
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000
配方
应用范围 WB,IHC-p,ELISA
别名 ACO 1,ACO1,ACOC,Aconitase 1 soluble,Aconitase,Aconitase1,Aconitate hydratase,ACONS,Citrate hydro lyase,Citrate hydro-lyase,Cytoplasmic aconitate hydratase,Ferritin repressor protein,IRE BP 1,IRE-BP 1,IREB 1,IREB1,IREBP,IREBP1,Iron regulatory protein 1,Iron responsive element binding protein 1,Iron-responsive element-binding protein 1,IRP 1,IRP1,OTTHUMP00000045233
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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