Anti-Human/Mouse/Rat MNAT1 Polyclonal Antibody

MNAT1多克隆抗体

Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminus domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II.
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基本信息

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货号 PA04844
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from the Internal region of human Mat1
特异性 Highest levels in colon and testis. Moderate levels are present thymus, prostate, ovary, and small intestine. The lowest levels are found in spleen and leukocytes.
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot P51948
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000
配方
应用范围 WB,IHC-p,ELISA
别名 MNAT 1,CAP35,CDK activating kinase assembly factor MAT1,CDK-activating kinase assembly factor MAT1,CDK7/cyclin H assembly factor,CDK7/cyclin-H assembly factor,Cyclin G1 interacting protein,Cyclin-G1-interacting protein,MAT1,MAT1,Menage a trois 1 (CAK assembly factor),Menage a trois,Menage a trois homolog 1,cyclin H assembly factor (Xenopus laevis),MNAT CDK activating kinase assembly factor 1,Mnat1,p35,p36,RING finger protein 66,RING finger protein MAT1,RNF66,TFB3
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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