This gene encodes a nuclear protein similar to the mouse double minute 1 protein. The mouse gene is located in double minute (DM) chromatin particles, is amplified in the mouse transformed 3T3 cell line, and the encoded protein is able to bind to p53. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.MDM1 (Mdm1 Nuclear Protein) is a Protein Coding gene. Diseases associated with MDM1 include Retinitis Pigmentosa 3.