Anti-Human/Mouse/Rat MAP3K7 Polyclonal Antibody

MAP3K7多克隆抗体

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
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基本信息

数据文档 查看数据文档
货号 PA07637
规格 100μl
宿主 Rabbit
免疫原 Fusion protein of human MAP3K7
特异性 Isoform 1A is the most abundant in ovary, skeletal muscle, spleen and blood mononuclear cells. Isoform 1B is highly expressed in brain, kidney and small intestine. Isoform 1C is the major form in prostate. Isoform 1D is the less abundant form.
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot O43318
浓度 0.3 mg/mL
推荐稀释度 IHC 1:10-50, ELISA 1:1000-2000
配方
应用范围 IHC,ELISA
别名 M3K7,MAP3K 7,Map3k7,MEKK7,Mitogen activated protein kinase kinase kinase 7,Mitogen-activated protein kinase kinase kinase 7,TAK1,TGF beta activated kinase 1,TGF-beta-activated kinase 1,TGF1a,Transforming growth factor beta activated kinase 1,Transforming growth factor-beta-activated kinase 1
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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