数据文档 | 查看数据文档 |
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货号 | PA04718 |
规格 | 100μl |
宿主 | Rabbit |
免疫原 | Synthesized peptide derived from human Lamin A/C around the non-phosphorylation site of Ser22. |
特异性 | In the arteries, prelamin-A/C accumulation is not observed in young healthy vessels but is prevalent in medial vascular smooth muscle celle (VSMCs) from aged individuals and in atherosclerotic lesions, where it often colocalizes with senescent and degenerate VSMCs. Prelamin-A/C expression increases with age and disease. In normal aging, the accumulation of prelamin-A/C is caused in part by the down-regulation of ZMPSTE24/FACE1 in response to oxidative stress. |
亚型 | IgG |
反应性 | Human,Mouse,Rat |
克隆 | |
Uniprot | P02545 |
浓度 | 1mg/mL |
推荐稀释度 | WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000 |
配方 | 应用范围 | WB,IHC-p,ELISA |
别名 | 70 kDa lamin,Cardiomyopathy dilated 1A (autosomal dominant),CDCD1,CDDC,CMD1A,CMT2B1,EMD2,FPL,FPLD,FPLD2,HGPS,IDC,Lamin A,Lamin A/C,Lamin A/C like 1,Lamin,Lamin C,Lamin-A/C,LDP1,LFP,LGMD1B,Limb girdle muscular dystrophy 1B (autosomal dominant),LMN 1,LMN A,LMN C,LMN1,LMNA,LMNA,LMNC,LMNL1,Prelamin A/C,PRO1,Renal carcinoma antigen NY REN 32,Renal carcinoma antigen NY-REN-32,Renal carcinoma antigen NYREN32 |
保存条件 | 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年. |
注意 | 仅用于科学研究, 不能用于疾病诊断. |
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