Anti-Human/Mouse/Rat LIMK1 Polyclonal Antibody

LIMK1多克隆抗体

Protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Stimulates axonal outgrowth and may be involved in brain development. Isoform 3 has a dominant negative effect on actin cytoskeletal changes.
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基本信息

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货号 PA04743
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from the Internal region of human LIMK-1
特异性 Highest expression in both adult and fetal nervous system. Detected ubiquitously throughout the different regions of adult brain, with highest levels in the cerebral cortex. Expressed to a lesser extent in heart and skeletal muscle.
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot P53667
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000
配方
应用范围 WB,IHC-p,IF,ELISA
别名 EC 2.7.1.37,LIM domain containing protein kinase,LIM domain kinase 1,LIM kinase,LIM motif containing protein kinase,LIMK 1,LIMK,LIMK-1,limk1,LIMK1
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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