Anti-Human/Mouse/Rat LIMK1 Polyclonal Antibody

LIMK1多克隆抗体

Protein kinase which regulates actin filament dynamics. Phosphorylates and inactivates the actin binding/depolymerizing factor cofilin, thereby stabilizing the actin cytoskeleton. Stimulates axonal outgrowth and may be involved in brain development. Isoform 3 has a dominant negative effect on actin cytoskeletal changes.
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基本信息

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货号 PA04742
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from human LIMK-1 around the non-phosphorylation site of T508.
特异性 Highest expression in both adult and fetal nervous system. Detected ubiquitously throughout the different regions of adult brain, with highest levels in the cerebral cortex. Expressed to a lesser extent in heart and skeletal muscle.
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot P53667
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, ELISA 1:20000
配方
应用范围 WB,IHC-p,ELISA
别名 EC 2.7.1.37,LIM domain containing protein kinase,LIM domain kinase 1,LIM kinase,LIM motif containing protein kinase,LIMK 1,LIMK,LIMK-1,limk1,LIMK1
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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