Anti-Human/Mouse/Rat LCK Polyclonal Antibody

LCK多克隆抗体

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described.
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基本信息

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货号 PA04732
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from human Lck around the non-phosphorylation site of S540.
特异性 Expressed specifically in lymphoid cells.
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot P06239
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, ELISA 1:40000
配方
应用范围 WB,ELISA
别名 IMD22,LCK,Lck p56,LCK proto-oncogene,Src family tyrosine kinase,LCK,Leukocyte C-terminal Src kinase,LSK,Lymphocyte cell specific protein tyrosine kinase,Lymphocyte cell-specific protein-tyrosine kinase,Lymphocyte specific protein tyrosine kinase,Membrane associated protein tyrosine kinase,Oncogene lck,P56 LCK,p56(LSTRA) protein tyrosine kinase,p56-LCK,p56lck,pp58 lck,pp58lck,Protein YT16,Proto oncogene tyrosine protein kinase LCK,Proto-oncogene Lck,Protooncogene tyrosine protein kinase LCK,T cell specific protein tyrosine kinase,T cell-specific protein-tyrosine kinase,T lymphocyte specific protein tyrosine kinase p56lck,Tyrosine-protein kinase Lck,YT 16,YT16
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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