Anti-Human/Mouse/Rat KCNA10 Polyclonal Antibody

KCNA10多克隆抗体

KCNA10 (Potassium Voltage-Gated Channel Subfamily A Member 10) is a Protein Coding gene. Among its related pathways are Potassium Channels and Transmission across Chemical Synapses. GO annotations related to this gene include ion channel activity and intracellular cyclic nucleotide activated cation channel activity. An important paralog of this gene is KCNA4.Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It is specifically regulated by cGMP and postulated to mediate the effects of substances that increase intracellular cGMP. This gene is intronless, and the gene is clustered with genes KCNA2 and KCNA3 on chromosome 1.
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基本信息

数据文档 查看数据文档
货号 PA04323
规格 100μl
宿主 Rabbit
免疫原 Synthetic Peptide
特异性 Detected in kidney, in proximal tubules, glomerular endothelium, in vascular endothelium and in smooth muscle cells.
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot Q16322
浓度 1mg/mL
推荐稀释度 WB 1:1000-2000, IHC 1:100-200
配方
应用范围 WB,IHC-p
别名 Cyclic GMP gated potassium channel,KCA10,Kcn 1,Kcn1,KCNA 10,KCNA10,Kv1.8,Potassium voltage gated channel shaker related subfamily member 10,Potassium voltage gated channel subfamily A member 10,Potassium voltage-gated channel subfamily A member 10,Voltage gated potassium channel subunit Kv1.8,Voltage-gated potassium channel subunit Kv1.8
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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