Anti-Human/Mouse/Rat FMR1 Polyclonal Antibody

FMR1多克隆抗体

The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.
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基本信息

数据文档 查看数据文档
货号 PA12082
规格 100μl
宿主 Rabbit
免疫原 Recombinant protein of human FMR1
特异性 Highest levels found in neurons, brain, testis, placenta and lymphocytes. Also expressed in epithelial tissues and at very low levels in glial cells.
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot Q06787
浓度 0.5 mg/mL
推荐稀释度 IHC 1:50-1:200
配方
应用范围 IHC,ELISA
别名 FMR 1,Fmr1,Fmr1 gene,FMR1,FMRP,Fragile X mental retardation 1,Fragile X mental retardation 1 protein,Fragile X mental retardation protein 1,Fragile X mental retardation protein,fragile X mental retardation syndrome-related protein 1,fragile X mental retardation,autosomal homolog 1,FRAXA,fxr1,MGC87458,POF,POF1,Protein FMR-1,Protein FMR1,wu:fb16f11,wu:fd18c10,zgc:66226
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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