Anti-Human/Mouse/Rat Fibulin 5 Polyclonal Antibody

Fibulin 5多克隆抗体

The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa, autosomal recessive cutis laxa type I (CL type I), and age-related macular degeneration type 3 (ARMD3).
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基本信息

数据文档 查看数据文档
货号 PA11177
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide of human FBLN5
特异性 Expressed predominantly in heart, ovary, and colon but also in kidney, pancreas, testis, lung and placenta. Not detectable in brain, liver, thymus, prostate, or peripheral blood leukocytes.
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot Q9UBX5
浓度 #N/A
推荐稀释度 IHC 1:50-1:200
配方
应用范围 IHC,ELISA
别名 ADCL2,ARCL1A,ARMD3,Dance,Developmental arteries and neural crest EGF like protein,Developmental arteries and neural crest EGF-like protein,EVEC,Fbln5,FBLN5,FIBL 5,FIBL-5,Fibulin-5,FLJ90059,UP50,Urine p50 protein
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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