Anti-Human/Mouse/Rat DCX Polyclonal Antibody

DCX多克隆抗体

Seems to be required for initial steps of neuronal dispersion and cortex lamination during cerebral cortex development. May act by competing with the putative neuronal protein kinase DCAMKL1 in binding to a target protein. May in that way participate in a signaling pathway that is crucial for neuronal interaction before and during migration, possibly as part of a calcium ion-dependent signal transduction pathway. May be part with LIS-1 of an overlapping, but distinct, signaling pathways that promote neuronal migration.
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基本信息

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货号 PA03579
规格 100μl
宿主 Rabbit
免疫原 Synthesized peptide derived from human Doublecortin around the non-phosphorylation site of S376.
特异性 Highly expressed in neuronal cells of fetal brain (in the majority of cells of the cortical plate, intermediate zone and ventricular zone), but not expressed in other fetal tissues. In the adult, highly expressed in the brain frontal lobe, but very low expression in other regions of brain, and not detected in heart, placenta, lung, liver, skeletal muscles, kidney and pancreas.
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot O43602
浓度 1mg/mL
推荐稀释度 WB 1:500-1:2000, ELISA 1:10000
配方
应用范围 WB,ELISA
别名 DBCN,Dbct,DC,DCX,DCX,Doublecortex,Doublin,FLJ51296,Lis X,Lis-X,Lissencephalin X,Lissencephalin-X,Lissencephaly X linked,Lissencephaly X linked doublecortin,LISX,Neuronal migration protein doublecortin,OTTHUMP00000023859,OTTHUMP00000023860,OTTHUMP00000216315,OTTHUMP00000216316,SCLH,XLIS
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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