Anti-Human/Mouse/Rat Cyclin D1 Polyclonal Antibody

Cyclin D1多克隆抗体

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance throughout the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activity is required for cell cycle G1/S transition. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification and overexpression of this gene, which alters cell cycle progression, are observed frequently in a variety of tumors and may contribute to tumorigenesis.
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基本信息

数据文档 查看数据文档
货号 PA11036
规格 100μl
宿主 Rabbit
免疫原 Synthetic peptide of human CCND1
特异性
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot P24385
浓度 0.5 mg/mL
推荐稀释度 IHC 1:10-1:50
配方
应用范围 IHC,ELISA
别名 AI327039,B cell CLL/lymphoma 1,B cell leukemia 1,B cell lymphoma 1 protein,B-cell lymphoma 1 protein,BCL 1,BCL-1,BCL-1 oncogene,BCL1,BCL1 oncogene,ccnd1,CCND1/FSTL3 fusion gene,included,CCND1/IGHG1 fusion gene,included,CCND1/IGLC1 fusion gene,included,CCND1/PTH fusion gene,included,CCND1,cD1,Cyl 1,D11S287E,G1/S specific cyclin D1,G1/S-specific cyclin-D1,Parathyroid adenomatosis 1,PRAD1,PRAD1 oncogene,U21B31
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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