Anti-Human/Mouse/Rat CRK Polyclonal Antibody

CRK多克隆抗体

This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.
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基本信息

数据文档 查看数据文档
货号 PA12314
规格 100μl
宿主 Rabbit
免疫原 Recombinant protein of human CRK
特异性
亚型 IgG
反应性 Human,Mouse,Rat
克隆
Uniprot P46108
浓度 0.4 mg/mL
推荐稀释度 IHC 1:50-1:200
配方
应用范围 IHC,ELISA
别名 Adapter molecule crk,Avian sarcoma virus CT10 (v crk) oncogene homolog,CRK,CRK isoform 2,CRK isoform II,CRK,CRKII,FLJ38130,OTTHUMP00000115366,OTTHUMP00000198330,p38,Proto oncogene C crk,Proto-oncogene C-crk,v crk avian sarcoma virus CT10 oncogene homolog,v crk sarcoma virus CT10 oncogene homolog,v crk sarcoma virus CT10 oncogene homolog (avian)
保存条件 冻干产品: 2 - 8°C保存5年; 液体: -20°C保存2年.
注意 仅用于科学研究, 不能用于疾病诊断.

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